01160nas a2200181   4500008004100000245011000041210006900151260000800220300001600228490000700244520048800251100002900739700001800768700001700786700002700803700002200830856012600852       2017                        eng d00aFacile synthesis of N-acyl 2-aminobenzothiazoles by NHC-catalyzed direct oxidative amidation of aldehydes0 aFacile synthesis of Nacyl 2aminobenzothiazoles by NHCcatalyzed d  cJAN  a1478 - 14810 v533 aA mild, general, and high yielding synthesis of N-acyl 2-aminobenzothiazoles has been demonstrated by N-heterocyclic carbene (NHC)-organocatalyzed direct amidation of aldehydes with 2-aminobenzothiazoles proceeding via acyl azolium intermediates. The carbene generated from the triazolium salt under oxidative conditions was the key for the success of this reaction. The method was subsequently applied to the synthesis of various biologically important N-acyl 2-aminobenzothiazoles.1 aPremaletha, Sethulekshmi1 aGhosh, Arghya1 aJoseph, Sumi1 aReddy, Santhi, Vardhan1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/facile-synthesis-n-acyl-2-aminobenzothiazoles-nhc-catalyzed-direct-oxidative-amidation01194nas a2200181   4500008004100000022001400041245012600055210006900181260000800250300001400258490000700272520051900279100002300798700001800821700002300839700002200862856012800884       2018                        eng d  a1523-706000aN-Heterocyclic carbene-catalyzed enantioselective synthesis of spiro-glutarimides via alpha,beta-unsaturated acylazoliums0 aNHeterocyclic carbenecatalyzed enantioselective synthesis of spi  cAUG  a4499-45030 v203 a<p>NHC-catalyzed enantioselective [3 + 3] spiro-annulation of alpha,beta-unsaturated aldehydes with cyclic beta-ketoamides allowing the preparation of synthetically and biologically important spiro-glutarimide derivatives has been reported. The interception of the ketoamides with catalytically generated chiral alpha,beta-unsaturated acylazoliums proceeds in a Michael addition-intramolecular amidation pathway to deliver the spirocyclic products with good yield, diastereoselectivity, and enantioselectivity.</p>1 aMondal, Santigopal1 aGhosh, Arghya1 aMukherjee, Subrata1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/n-heterocyclic-carbene-catalyzed-enantioselective-synthesis-spiro-glutarimides-alphabeta01319nas a2200181   4500008004100000022001400041245013800055210006900193260000800262300001400270490000700284520063000291100002300921700001800944700002600962700002200988856012701010       2018                        eng d  a1523-706000aN-Heterocyclic carbene-catalyzed michael-michael-lactonization cascade for the enantioselective synthesis of tricyclic delta-lactones0 aNHeterocyclic carbenecatalyzed michaelmichaellactonization casca  cMAY  a2952-29550 v203 a<p>Enantioselective synthesis of tricyclic delta-lactones with three contiguous stereocenters has been demonstrated by the N-heterocyclic carbene (NHC)-catalyzed functionalization of benzylic C(sp(3))-H bonds. The NHC-catalyzed reaction of enals with dinitrotoluene derivatives under oxidative conditions proceeds via the chiral alpha,beta-unsaturated acylazoliums and produces the delta-lactones in good yields and excellent diastereoselectivity and enantioselectivity. This mild and atom-economic cascade reaction takes place in a Michael/Michael/lactonization sequence and tolerates a broad range of functional groups.</p>1 aMukherjee, Subrata1 aGhosh, Arghya1 aMarelli, Udaya, Kiran1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/n-heterocyclic-carbene-catalyzed-michael-michael-lactonization-cascade-enantioselective01164nas a2200181   4500008004100000022001400041245012700055210006900182260000900251300001400260490000700274520048900281100001800770700001700788700002300805700002200828856013200850       2019                        eng d  a0022-326300aSynthesis of 2-Aryl naphthoquinones by the cross-dehydrogenative coupling involving an NHC-catalyzed endo-stetter reaction0 aSynthesis of 2Aryl naphthoquinones by the crossdehydrogenative c  cJAN   a1103-11100 v843 a<p>An N-heterocyclic carbene (NHC)-catalyzed intramolecular Stetter reaction proceeding via the endo-fashion was the key step for the transition-metal-free and mild cross-dehydrogenative coupling of 2-cinnamoyl benzal-dehydes allowing for the synthesis of 2-aryl naphthoquinones. In this transformation, the carbene generated from the triazolium salt using Na2CO3 catalyzes the intramolecular Stetter reaction, which was followed by air oxidation to reinstall the C-C double bond.</p>1 aGhosh, Arghya1 aPatra, Atanu1 aMukherjee, Subrata1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/synthesis-2-aryl-naphthoquinones-cross-dehydrogenative-coupling-involving-nhc-catalyzed-endo01399nas a2200193   4500008004100000022001400041245015900055210006900214260000900283300001400292490000700306520066400313100001800977700001600995700001801011700002401029700002201053856013001075       2021                        eng d  a1523-706000aEnantioselective synthesis of 5,6-dihydroindolizines by N-heterocyclic carbene (NHC)-catalyzed core-structure-inspired strategy of azolium-enolate cascade0 aEnantioselective synthesis of 56dihydroindolizines by Nheterocyc  cJUL   a5223-52280 v233 aThe core-structure motivated design has allowed the enantioselective synthesis of 5,6-dihydroindolizines via N-heterocyclic carbene (NHC) catalysis. The NHC-catalyzed reaction of alpha,beta-unsaturated aldehydes with the suitably substituted pyrrole derivatives proceed via the initial generation of alpha,beta-unsaturated acylazoliums from enals, and enolates from pyrroles and the reaction culminated in an efficient cascade process involving the Michael-aldol-lactonization-decarboxylation sequence to afford the products in reasonable yields and high selectivities. The method is further extended to the construction of spirocyclic 5,6-dihydroindolizines.1 aGhosh, Arghya1 aShee, Sayan1 aBarik, Shilpa1 aGonnade, Rajesh, G.1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/enantioselective-synthesis-56-dihydroindolizines-n-heterocyclic-carbene-nhc-catalyzed-core