01835nas a2200217   4500008004100000022001400041245005600055210005600111260000800167300001000175490000700185520121100192653001201403653003101415653001201446653001201458653001801470100002601488700002001514856008301534       2018                        eng d  a0959-810300aInteraction of polymers with amyloidogenic peptides0 aInteraction of polymers with amyloidogenic peptides  cJAN  a15-240 v673 a<p>With this review, the aim was to gather recent representative publications which describe the interaction of polymers with amyloidogenic peptides/proteins. When functional, these take part in for instance bacterial adhesion and biofilm formation. However, several of the peptides/proteins have been identified in various diseases. One of the current approaches to discover a cure against these relies on therapeutics which either prevent or accelerate peptide/protein aggregation and/or clear readily formed aggregates. Owing to the common interest of scientists from all disciplines to identify a cure against the diseases of public health concern, there are overwhelming numbers of publications dealing with these two approaches. Since amyloid aggregation could be regarded as a nucleated polymerization, which is an established mechanism of polymer self-assembly, we recently tackled the issue of amyloid aggregation using the theories and methods established in polymer science. In this review, we hence focus on gathering relevant and recent publications which describe the role of polymers in modulating the aggregation of amyloidogenic peptides/proteins. (c) 2017 Society of Chemical Industry</p>10aamyloid10aneurodegenerative diseases10aPolymer10aprotein10aSelf-assembly1 aAbraham, Jancy, Nixon1 aNardin, Corinne  uhttps://library.ncl.res.in/content/interaction-polymers-amyloidogenic-peptides01634nas a2200217   4500008004100000022001400041245011900055210006900174260000800243300001200251490000600263520088000269653001301149653002301162653002101185653001801206653001501224100002301239700002601262856012801288       2018                        eng d  a2365-654900aNovel pentadecyl phenol-tagged L-tryptophan molecules: synthesis, self- assembly and liquid crystalline properties0 aNovel pentadecyl phenoltagged Ltryptophan molecules synthesis se  cJAN  a108-1150 v33 a<p>The paper describes the self-assembly and liquid crystalline properties of pentadecylphenol tagged L-tryptophan molecules having ester and amide functionality. We have synthesized a series of molecules having mono and ditryptophan moieties attached to pentadecylphenol through amide or ester linkage. The fluorescence properties of the Boc-L-tryptophan-pentadecylphenol molecules were measured in methanol and found to aggregate beyond the critical aggregation concentration and self-assembled to give spherical structures. Upon deprotection of Boc group, the amine end group got involved in extended hydrogen bonding and fibril like structures were developed. These molecules also showed liquid crystalline behavior in hydrogen bonding solvents such as benzyl alcohol and showed needle like crystals in tert-butanol, as analyzed by polarized optical light microscopy.</p>10aCardanol10aliquid crystalline10apentadecylphenol10aSelf-assembly10aTryptophan1 aParappurath, Akhil1 aAbraham, Jancy, Nixon  uhttps://library.ncl.res.in/content/novel-pentadecyl-phenol-tagged-l-tryptophan-molecules-synthesis-self-assembly-and-liquid