01424nas a2200157   4500008004100000022001400041245011700055210006900172260000800241300001400249490000700263520081700270100002401087700002801111856012701139       2026                        eng d  a1477-052000aOne-pot synthesis of N-arylated benzotriazoles and benzotriazinones via in situ diazotization and aryne trapping0 aOnepot synthesis of Narylated benzotriazoles and benzotriazinone  cJUN  a4696-47110 v243 a<p>
	N-Arylated benzotriazoles and 1,2,3-benzotriazin-4-ones are important structural motifs in synthetic and medicinal chemistry, valued for their distinctive frameworks and functional versatility. We have developed an efficient, one-pot strategy for the synthesis of N-arylated benzotriazoles and benzotriazinones. The protocol involves in situ diazotization of o-phenylenediamine or 2-aminobenzamide using tert-butyl nitrite (tBuONO), followed by trapping of arynes generated in situ from 2-(trimethylsilyl)aryltriflates in the presence of CsF. The methodology exhibits broad functional-group tolerance and was successfully applied to 47 substrates, affording yields in the range of 60-85%. Furthermore, gram-scale synthesis highlights the operational simplicity and practical utility of this approach.</p>
1 aGhodake, Balaji, M.1 aBhattacharya, Asish, K.  uhttps://library.ncl.res.in/content/one-pot-synthesis-n-arylated-benzotriazoles-and-benzotriazinones-situ-diazotization-and