03438nas a2200181 4500008004100000245011500041210006900156260000800225300001400233490000600247520276100253100001803014700003103032700001903063700002203082700002103104856013103125 2025 eng d00aImmobilization of aldehyde reductase for the production of bioplastic precursors from agricultural fatty acids0 aImmobilization of aldehyde reductase for the production of biopl cJUL a3910-39140 v33 a
Herein, we report the biosynthesis of bioplastic precursors thourgh the immobilization of aldehyde reductase (AHR) onto a metal organic framework (UIO-66-NH2). Kinetic analysis demonstrated that the immobilized AHR maintained significant catalytic activity and exhibited improved operational stability, as well as higher reusability, compared with the free AHR. Furthermore, the synthetic applicability of the immobilized AHR was evaluated in tandem with that of transaminase derived from S. pomeroyi (spTA), where 8, 10, and 12 carbon chain ω-amino fatty acids (ω-AFAs) were biosynthesized from the corresponding hydroxy fatty acids (ω-HFAs) with ∼90% conversions.
Herein, we report the biosynthesis of bioplastic precursors via the immobilization of aldehyde reductase (AHR) onto a metal organic framework (UIO-66-NH2).

 

1 aMohne, Devesh1 aReddy, Yeddula, Nikhileshw1 aRawat, Kshitij1 aPatil, Mahesh, D.1 aBhaumik, Jayeeta uhttps://library.ncl.res.in/content/immobilization-aldehyde-reductase-production-bioplastic-precursors-agricultural-fatty-acids