01329nas a2200169   4500008004100000022001400041245015300055210006900208260000800277300001400285490000700299520065300306100002700959700002800986700002401014856012101038       2025                        eng d  a1477-052000aEfficient synthesis of functionalized alkylidenephthalides, butenolides, pyranones, and isocoumarins via I2-PPh3: synthesis of Thunberginols A and F0 aEfficient synthesis of functionalized alkylidenephthalides buten  cAUG  a7702-77080 v233 a<p>A simple and efficient synthesis of functionalized alkylidenephthalides, butenolides, pyranones, and isocoumarins was achieved using I2-PPh3-Et3N reagent combination. The products obtained through this method act as versatile components in organic synthesis, enabling further modifications of functional groups. This method exhibits a wide substrate scope, employs straightforward and cost-effective reagents, eliminates the need for acidic, carbodiimide or other coupling agents, and operates at ambient temperature. Moreover, this methodology has been successfully applied to the synthesis of two natural products, Thunberginols A and F.</p>
1 aAbhang, Rohitkumar, V.1 aBhagwat, Prathamesh, N.1 aHandore, Kishor, L.  uhttps://library.ncl.res.in/content/efficient-synthesis-functionalized-alkylidenephthalides-butenolides-pyranones-and