02521nas a2200217   4500008004100000022001400041245016800055210006900223260000900292300001400301490000700315520171300322100002202035700001502057700002402072700001702096700001702113700002402130700002402154856012502178       2024                        eng d  a2050-752600aUnravelling polymorphism-driven luminescence in GFP chromophore analogues: insights into the phase transition and morphology-dependent optical waveguide properties0 aUnravelling polymorphismdriven luminescence in GFP chromophore a  cJUN   a8368-83790 v123 a<p>
	The advent of multi-emission organic solid-state materials in response to external stimuli has sparked the scientific community due to their potential application in developing sophisticated optoelectronic sensors and bioanalytical tools. This article presents green fluorescent protein chromophore (GFPc) analogue-based polymorphs exhibiting significantly different emissions due to various noncovalent interactions in the supramolecular environment and conformational alterations in the crystalline state. In both compounds (A and B), the polymorphs undergo monotropic thermal phase transitions that are characterized by DSC, HSM, and VT-PXRD techniques. The distinct fluorescent emission characteristics of these polymorphs demonstrated morphology-related optical waveguiding features. Specifically, the plate-type Form A1 emitted light with a 2D blue hue, while the needle-type Form A2 emitted light with a yellowish-green colour. Additionally, the impressive waveguiding capabilities of Form B1 were explored in both straight and singly/doubly bending configurations to facilitate fluorescence propagation. Consequently, there is significant interest in developing organic materials based on GFP chromophores, which exhibit low emission in solution but display multi-fluorescent emission in the solid state. These materials are promising for applications such as optoelectronic devices, security tags, live cell imaging, and fluorescent inks. Polymorphs of GFPc analogs A and B display differences in their optical waveguiding properties in 1D and 2D depending on the crystal shapes. Furthermore, Form B1 demonstrates efficient optical waveguiding capabilities even when the crystal is bent.</p>
1 aDabke, Niteen, B.1 aRaut, Yash1 aMali, Bhupendra, P.1 aPandya, Rinu1 aVanka, Kumar1 aManoj, Kochunnoonny1 aGonnade, Rajesh, G.  uhttps://library.ncl.res.in/content/unravelling-polymorphism-driven-luminescence-gfp-chromophore-analogues-insights-phase