01695nas a2200217   4500008004100000022001400041245010700055210006900162260000800231490000700239520093400246653001801180653003001198653001601228653002601244100002201270700002101292700002201313700002201335856012001357       2024                        eng d  a2193-580700aVisible-light mediated C-3 amination of quinoxalin-2(1H)-ones via electron donor-acceptor complexation0 aVisiblelight mediated C3 amination of quinoxalin21Hones via elec  cAUG0 v133 a<p>
	The formation of carbon-nitrogen bonds holds paramount importance in the realm of synthetic organic chemistry, finding extensive applications in the synthesis of pharmaceuticals, agrochemicals, and organic materials. Herein, we describe a novel EDA complex mediated, metal- and photocatalyst-free, visible-light-initiated direct C-3 amination of biologically important, quinoxalin-2(1H)-one moiety. The key to the success lies in the formation of a photoactivated electron donor-acceptor complex between quinoxalin-2(1H)-one and amine, which undergo subsequent electron transfer reaction to effect the desired transformation. A diverse array of 3-aminoquinoxalin-2(1H)-ones were prepared employing this process and the yields are up to 87%. This work represents a significant advancement toward a more environmentally friendly and efficient approach, characterized by mild reaction conditions and a high atom economy.</p>
10aC-3 amination10aDehydrogenative amination10aEDA complex10aquinoxalin-2(1H)-ones1 aMore, Devidas, A.1 aGayathri, P., R.1 aThete, Kishor, R.1 aMuthukrishnan, M.  uhttps://library.ncl.res.in/content/visible-light-mediated-c-3-amination-quinoxalin-21h-ones-electron-donor-acceptor