00976nas a2200193 4500008004100000245006800041210006800109260000800177300001400185490000700199520034000206100001900546700001900565700002600584700002400610700002400634700002400658856010000682 2023 eng d00aPolymorph II of hydroxyurea 150 years after its first synthesis0 aPolymorph II of hydroxyurea 150 years after its first synthesis cMAY a2712-27160 v253 a

A new polymorph of hydroxyurea (HU) was crystallized 150 years after its first synthesis. Due to its medicinal use in neoplastic diseases and sickle cell anemia, a high throughput screen of HU binary cocrystals was attempted. Instead of a cocrystal, an isoenergetic form II crystallized concomitantly with urea in methanol.

1 aRai, Sunil, K.1 aTothadi, Srinu1 aArhangelskis, Mihails1 aGeorge, Christy, P.1 aGonnade, Rajesh, G.1 aNangia, Ashwini, K. uhttps://library.ncl.res.in/content/polymorph-ii-hydroxyurea-150-years-after-its-first-synthesis