01562nas a2200217   4500008004100000022001400041245014000055210006900195260000900264300001100273490000800284520076300292653002101055653002201076653002501098653002801123653002101151100002801172700002201200856012201222       2023                        eng d  a0040-403900aBismuth(III)-catalyzed cascade condensation of alkynyl alcohols with terminal alkynes: a facile construction of propargyl cyclic ethers0 aBismuthIIIcatalyzed cascade condensation of alkynyl alcohols wit  cJAN   a1542740 v1143 a<p>
	Herein, we report a Bi(OTf)3-catalyzed cascade condensation between alkynols (particularly pent-4-yn-1ols and hex-5-yn-1-ols) and terminal alkynes (aryl alkynes) to facile access to diverse propargyl cyclic ethers (2 alkynyl tetrahydrofurans and 2 alkynyl tetrahydropyrans). This simple and efficient cascade transformation proceeds through initial intramolecular hydroalkoxylation of alkynols to give corresponding cyclic enol ethers (via exo-dig or endo-dig mode of ring-closure) followed by hydroalkynylation. Costeffective, naturally abundant, green Lewis acid catalysis, ambient reaction conditions, short reaction times, good substrate scope, and high yields are salient features of this strategy.(c) 2022 Elsevier Ltd. All rights reserved.</p>
10aAlkynyl alcohols10aBismuth catalysis10aCascade condensation10aPropargyl cyclic ethers10aTerminal alkynes1 aPratapure, Madhukar, S.1 aKontham, Ravindar  uhttps://library.ncl.res.in/content/bismuthiii-catalyzed-cascade-condensation-alkynyl-alcohols-terminal-alkynes-facile