11345nas a2200157 45000080041000002450092000412100069001332600008002023000011002104900006002215201076200227100002410989700002611013700002511039856012311064 2022 eng d00aCobalt-immobilized carbon-based nano-catalyst for Csingle bondN cross coupling reaction0 aCobaltimmobilized carbonbased nanocatalyst for Csingle bondN cro cJAN a1006820 v43 a

Csingle bondcross coupling reaction is very important in synthesis of pharmaceuticals, natural productsagrochemicals, fine chemicals and functional materials. Traditionally, palladium or copper metals are used for Csingle bondN coupling reaction. As palladium is expensive, we developed cobalt immobilized carbon-based nano-catalyst Co@CC for Csingle bondN coupling. In this work, we synthesized non-noble metal-based Co@CC nano-catalyst by carbonization of glucose, it’s functionalization followed by immobilization of cobalt on the surface of the catalyst. The catalyst was well characterized. The Csingle bondN cross coupling reaction of various aryl halides & amines using Co@CC nano-catalyst was optimized for solvent, reaction temperature & catalyst concentration conditions. The catalyst showed high catalytic activity for Csingle bondN coupling of various aryl halides & amines to form aryl amines in good to excellent yield up to 91 % in sulfolane as a solvent at 150 °C. The catalyst showed recyclability up to 5 times. The method developed for Csingle bondN coupling reaction was noble metal free, ligand free, recyclable, sustainable, economical & environmentally friendly.

1 aBankar, Shubham, R.1 aKirdant, Swapnali, P.1 aJadhav, Vrushali, H. uhttps://library.ncl.res.in/content/cobalt-immobilized-carbon-based-nano-catalyst-csingle-bondn-cross-coupling-reaction