01273nas a2200229 4500008004100000022001400041245006800055210006700123260000800190490000700198520059100205653001600796653002300812653001300835653002000848653001400868100001900882700001700901700001800918700001800936856008900954 2023 eng d a1434-193X00aOrganophosphites: an addition to the arsenal of organocatalysts0 aOrganophosphites an addition to the arsenal of organocatalysts cJAN0 v263 a

Organophosphites are nucleophilic in nature and can act as a good leaving group owing to the stability of the phosphite anion. This dual reactivity makes them good candidates for nucleophilic organocatalysis. However, phosphites were introduced only in 2004 as the umpolung catalyst for acylsilane substrates utilizing sequential Brook rearrangements. Very recently, phosphites have been reported to catalyze aza-rearrangements and radical reactions. In this review, we discuss the reactivity parameters to understand its lack of use, as well as the potential for catalysis.

10aacylradical10aazaacyl equivalent10acylanion10aorganocatalysis10aphosphite1 aBaral, Nilofar1 aRani, Soniya1 aSaikia, Pinku1 aMaity, Pradip uhttps://library.ncl.res.in/content/organophosphites-addition-arsenal-organocatalysts