02034nas a2200241   4500008004100000022001400041245014700055210006900202260000800271300001400279490000700293520120200300653001401502653001401516653001301530653001501543653002401558100002401582700002401606700001801630700002201648856012201670       2022                        eng d  a2168-048500aEfficient synthesis of 5-(hydroxymethyl)furfural esters from polymeric carbohydrates using 5-(chloromethyl)furfural as a reactive intermediate0 aEfficient synthesis of 5hydroxymethylfurfural esters from polyme  cMAY  a5803-58090 v103 a<p>
	This work reports an efficient, gram-scale synthesis of 5-(hydroxymethyl)furfural (HMF) esters using biomass-derived 5-(chloromethyl)furfural (CMF) as a reactive intermediate. The HMF-esters have potential applications as chemicalintermediates, fuel additives, and bioactive compounds. Initially, CMF was prepared in good yields directly from polymericcarbohydrates (starch, inulin, and cellulose) and cellulosic materials (cotton andfilter paper) using a biphasic batch reaction system,consisting of aqueous hydrochloric acid and 1,2-dichloroethane. The use of ZnCl2as an additive allowed the reaction to proceedunder milder conditions while significantly improving the isolated yield of CMF. The effects of reaction temperature, reaction time,extracting solvent, and ZnCl2loading on CMF yield were investigated. Microcrystalline cellulose was converted into CMF with a72% isolated yield under optimized reaction conditions (80 degrees C, 2 h). After that, CMF was transformed into various novel esters ofHMF in excellent isolated yields (&gt;85%) by reacting with a slight excess amount of the triethylammonium salt of various alkyl/arylcarboxylic acids under solvent-free conditions</p>
10acatalysis10acellulose10afuranics10aHMF-esters10arenewable synthesis1 aBhat, Navya, Subray1 aHegde, Shobhita, L.1 aDutta, Saikat1 aSudarsanam, Putla  uhttps://library.ncl.res.in/content/efficient-synthesis-5-hydroxymethylfurfural-esters-polymeric-carbohydrates-using-5