02309nas a2200253   4500008004100000022001400041245015900055210006900214260000800283300001200291490000700303520144900310653001701759653001101776653001401787653001401801653001401815653001301829100001901842700001801861700002101879700002401900856013101924       2022                        eng d  a0972-593800aPharmaceutical standardization and physicochemical characterization of traditional ayurvedic mineral drug red ochre roasted in cow's ghee (Shuddha Gairik)0 aPharmaceutical standardization and physicochemical characterizat  cAPR  a303-3160 v213 a<p>
	Rasashastra is a pharmaceutics branch of Ayurveda describing scientific methods to convert metals and minerals into bio-compatible formulations used individually or plant admixed to enhance their bioavailability and efficacy. In the present study, red ochre (Gairik) powder was processed in cow's ghee by textual method of roasting. The steps of preparation and changes in the properties therein were documented and validated in triplicate batches to develop a monograph. Ayurvedic and basic tests were performed to determine the properties of Shuddha Gairik. The physical characterization included Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infra-red (FT-IR), Dynamic Light Scattering (DLS) and Thermo-gravimetric Analysis (TGA). Elemental composition was estimated by titration and gravimetric analysis while heavy metal limits were assessed using Inductively Coupled Plasma Optical Emission Spectrophotometry (ICPOES). This study depicted that crude red ochre, containing Kaolinite with high iron percentage, on roasting in cow's ghee led to the formation of fatty acids adsorbed red ochre particles. The developed monograph will be a guideline to the Ayurvedic industry for precise formulation of Shuddha Gairik. This will help researchers for better understanding the importance of Ayurvedic methods of pharmaceutical preparations and carry out their mechanistic studies in various diseases.</p>
10aFerric oxide10aGairik10aKaolinite10aMonograph10aRed ochre10aRoasting1 aChavan, S., B.1 aGupta, V., S.1 aDeshmukh, V., V.1 aSardeshmukh, S., P.  uhttps://library.ncl.res.in/content/pharmaceutical-standardization-and-physicochemical-characterization-traditional-ayurvedic-0