01192nas a2200229 4500008004100000022001400041245011500055210006900170260000800239300001500247490000600262520040700268653001900675653001900694653001900713653001500732653002600747100002200773700001600795700002200811856012900833 2022 eng d a2365-654900aMetal- and light-free direct C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols in aqueous medium0 aMetal and lightfree direct C3 ketoalkylation of quinoxalin21Hone cOCT ae2022035970 v73 a

Direct oxidative C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols using ammonium persulfate in an aqueous medium has been achieved in a moderate to good yield. The reaction does not require metals, light-source, or catalysts to facilitate the reaction and could be efficiently utilized to construct a wide range of biologically relevant 3-ketoalkylated quinoxalin-2(1H)-ones.

10aaqueous medium10acyclopropanols10aketoalkylation10ametal-free10aquinoxalin-2(1H)-ones1 aMore, Devidas, A.1 aMujahid, M.1 aMuthukrishnan, M. uhttps://library.ncl.res.in/content/metal-and-light-free-direct-c-3-ketoalkylation-quinoxalin-21h-ones-cyclopropanols-aqueous