01631nas a2200193   4500008004100000022001400041245015300055210006900208260000900277300001400286490000700300520087800307100002501185700002101210700002801231700002301259700002601282856012901308       2022                        eng d  a1144-054600aDiethyl phosphite-mediated switchable synthesis of bis(imidazoheterocycles) derived disulfanes and sulfanes using imidazoheterocycles and octasulfur0 aDiethyl phosphitemediated switchable synthesis of bisimidazohete  cMAR   a4784-47910 v463 a<p>
	A practical and highly efficient oxidative dual C-H sulfenylation of imidazoheterocycles using odorless, inexpensive elemental sulfur in DMSO to synthesize sulfur-bridged imidazoheterocycles under metal-free conditions is reported. The amount of diethyl phosphite and sulfur powder most attractively permits a tunable synthesis of bis(imidazoheterocycle)disulfanes and bis(imidazoheterocycle)sulfanes in good to high yields. A comprehensive substrate scope with a broad range of functional group tolerance was realized, and the efficacy of the process was proved at gram-scale reactions. Next, the bis(imidazopyridine)disulfanes were smoothly reacted with various indoles under similar conditions to form the corresponding imidazo[1,2-a]pyridine-indole-derived thioethers in high yields. A plausible mechanism has been proposed based on the control experiments.</p>
1 aReddy, Raju, Jannapu1 aShankar, Angothu1 aKumar, Jangam, Jagadesh1 aSharadha, Nunavath1 aKrishna, Gamidi, Rama  uhttps://library.ncl.res.in/content/diethyl-phosphite-mediated-switchable-synthesis-bisimidazoheterocycles-derived-disulfanes