01076nas a2200145   4500008004100000245013700041210006900178260000800247300001600255490000700271520047500278100002600753700002400779856012700803       2021                        eng d00aWittig reactions of maleimide-derived stabilized ylides with alkyl pyruvates: concise approach to methyl ester of (±)-chaetogline A0 aWittig reactions of maleimidederived stabilized ylides with alky  cAPR  a2897–29020 v533 aA facile synthesis of methyl ester of chaetogline A is reported starting from the corresponding methyl 1-methyltryptophanate-derived­ maleimide. A stereoselective Wittig olefination with a carbonyl function in methyl pyruvate followed by phosphorous pentoxide-induced­ regioselective dehydrative cyclization are the essential reactions. An acid-induced thermodynamically driven stereoselective β- to α-position migration of the exocyclic C=C bond unit in ethyl… 
1 aArgade, Narshinha, P.1 aShelar, Santosh, V.  uhttps://library.ncl.res.in/content/wittig-reactions-maleimide-derived-stabilized-ylides-alkyl-pyruvates-concise-approach-0