06595nas a2200181 4500008004100000245009800041210006900139260000900208300001200217490000700229520596300236100001706199700001506216700001906231700001806250700001906268856012606287 2021 eng d00aNanoparticles of biotite mica as Krishna Vajra Abhraka Bhasma: synthesis and characterization0 aNanoparticles of biotite mica as Krishna Vajra Abhraka Bhasma sy cJUN  a269-2820 v123 a

Background

Bio-inorganic nanoparticles or metal nanoparticles are used in medicine for diagnostic and treatment purposes. The nanomedicines from traditional Ayurvedic system are termed as bhasma. Rasashastra, the branch of inorganic medicines of Ayurveda, has documented monographs of metal-mineral bhasmas as potent drugs. However there is lack of scientific analytical data of the end products.

Objectives

Present study was aimed at finding out the morphological, structural, elemental and chemical composition of the Krishna vajra abhraka bhasma (KVB).

Materials and methods

Bhasma of KVB (Biotite Mica) was prepared in our laboratory using biotite mica sheets befitting selection criteria and carrying out further processes with strict SOPs as per AFI.

Results

The bhasma complied with the confirmatory tests from Rasashastra. The physical and physicochemical tests correlate with the results obtained by instrumental analytical methods. SEM revealed square shaped nanoparticles of mean size of 92.3 nm. EDAX showed presence of Si, Mg, O, Fe, Ca, Na, C, K and Al. XRD revealed the crystalline nature of bhasma with mixture of various individual oxides and spinel shape of the crystal. DLS showed that the nanoparticles are unimodal in nature. FTIR and NMR showed the organic functional groups obtained from cow milk and selected herbs, indicating unique bio-inorganic nature of the KVB.

 

1 aWele, Asmita1 aSourav, De1 aDalvi, Madhuri1 aDevi, Nandini1 aPandit, Vijaya uhttps://library.ncl.res.in/content/nanoparticles-biotite-mica-krishna-vajra-abhraka-bhasma-synthesis-and-characterization