01572nas a2200193   4500008004100000022001400041245013700055210006900192260000900261300001400270490000700284520085300291100001801144700002301162700002301185700001801208700002401226856012801250       2020                        eng d  a1367-480300aFunGeCo: a web-based tool for estimation of functional potential of bacterial genomes and microbiomes using gene context information0 aFunGeCo a webbased tool for estimation of functional potential o  cAPR   a2575-25770 v363 a<p>Motivation: Functional potential of genomes and metagenomes which are inferred using homology-based methods are often subjected to certain limitations, especially for proteins with homologs which function in multiple pathways. Augmenting the homology information with genomic location of the constituent genes can significantly improve the accuracy of estimated functions. This can help in distinguishing cognate homolog belonging to a candidate pathway from its other homologs functional in different pathways. Results: In this article, we present a web-based analysis platform `FunGeCo' to enable gene-context-based functional inference for microbial genomes and metagenomes. It is expected to be a valuable resource and complement the existing tools for understanding the functional potential of microbes which reside in an environment.</p>
1 aAnand, Swadha1 aKuntal, Bhusan, K.1 aMohapatra, Anwesha1 aBhatt, Vineet1 aMande, Sharmila, S.  uhttps://library.ncl.res.in/content/fungeco-web-based-tool-estimation-functional-potential-bacterial-genomes-and-microbiomes