01828nas a2200145 4500008004100000245011600041210006900157260000800226520122000234100002601454700002201480700002401502700002601526856013001552 2019 eng d00aAgNO3-Catalysed intramolecular cyclization: access to functionalized cyclopentanones and spiro-cyclopentanones 0 aAgNO3Catalysed intramolecular cyclization access to functionaliz cAUG3 a

An efficient AgNO3-catalysed method has been developed for the synthesis of functionalized cyclopentanones and spiro-cyclopentanones through intramolecular cyclization between ynones and cyanoacrylate/aryl/alkylidene malononitrile using DBU as a base. Easy availability of starting materials and mild reaction conditions makes this protocol more feasible over previously reported methods. The functionalized cyclopentanones and spiro-cyclopentanones were synthesized in good to excellent yields with a broad substrate scope.

1 aBhoite, Shubhangi, P.1 aBansode, Ajay, H.1 aBurate, Pralhad, A.1 aSuryayanshi, Gurunath uhttps://library.ncl.res.in/content/agno3-catalysed-intramolecular-cyclization-access-functionalized-cyclopentanones-and-spiro