00982nas a2200169 4500008004100000022001400041245011900055210006900174260000900243300001400252490000700266520034400273100002000617700002500637700002500662856012500687 2019 eng d a1477-922600aManganese-catalyzed direct C-C coupling of -C-H bonds of amides and esters with alcohols via hydrogen autotransfer0 aManganesecatalyzed direct CC coupling of CH bonds of amides and  cJUN  a7094-70990 v483 a

Herein we report an efficient manganese-catalyzed C-alkylation of unactivated amides and tert-butyl acetate using alcohols as alkylating agents. This elegant approach exhibits a broad substrate scope providing the C-C coupled products of amides via a hydrogen auto-transfer strategy using aryl, heteroaryl, and aliphatic alcohols.

1 aRana, Jagannath1 aGupta, Virendrakumar1 aBalaraman, Ekambaram uhttps://library.ncl.res.in/content/manganese-catalyzed-direct-c-c-coupling-c-h-bonds-amides-and-esters-alcohols-hydrogen