02260nas a2200241   4500008004100000022001400041245016300055210006900218260000800287300001600295490000700311520140300318653001901721653001401740653001601754653002601770653001301796653001401809100002601823700002801849700002101877856012001898       2016                        eng d  a1944-399400aMechanistic and spectroscopic investigations of Ru3+-catalyzed oxidative degradation of azidothymidine by heptavalent manganese at environmentally relevant pH0 aMechanistic and spectroscopic investigations of Ru3catalyzed oxi  cDEC  a28349-283620 v573 a<p>The rapid increase in the population across the world has increased the consumption of pharmaceutical substances. These pharmaceutical substances have penetrated into the water through various ways. Mechanistic and spectroscopic investigations of Ru3+-catalyzed oxidative degradation of azidothymidine (AZT) by heptavalent manganese was studied for the first time. The values of pH-dependent apparent second-order rate constant show that Ru3+ accelerates the rate of the oxidative degradation of AZT by heptavalent manganese eight times faster than uncatalyzed reaction. Ru3+ catalytic oxidative degradation of AZT by heptavalent manganese was greatly depending on the pH. The removal of the AZT by heptavalent manganese in the presence of Ru3+ shows unit order with respect to heptavalent manganese, Ru3+, and AZT. The influences of dielectric constant, ionic strength, pH, addition of monomer, variation in catalyst concentration, etc. on the rate of the reaction were studied thoroughly and discussed in detail. The eight different products produced during the reaction were analyzed using the high-resolution mass spectrometry. Activation parameters were determined from variation in temperature during the reaction. The catalytic plausible mechanism was projected in which Ru3+ is oxidized to higher oxidation states of ruthenium by heptavalent manganese at environmentally relevant pH.</p>10aAzidothymidine10acatalysis10aDegradation10aHeptavalent manganese10akinetics10aMechanism1 aKulkarni, Raviraj, M.1 aBhamare, Vijaykumar, S.1 aSanthakumari, B.  uhttps://library.ncl.res.in/content/mechanistic-and-spectroscopic-investigations-ru3-catalyzed-oxidative-degradation