01751nas a2200157   4500008004100000245018200041210006900223300001400292490000800306520108200314100001401396700001901410700001901429700001401448856013101462       2018                        eng d00aCatalytic and efficient synthesis of optically active terminal epoxides and 1,2-diols using a new lanthanum triflate assisted C1-symmetric bimetallic chiral salen cobalt complex0 aCatalytic and efficient synthesis of optically active terminal e  a960 - 9660 v15 3 aThe catalytic asymmetric synthesis of terminal epoxides and 1,2-diols via a hydrolytic kinetic resolution of racemic terminal epoxides using a new bimetallic chiral salen CoIII complex incorporated with La(OTf)3 as a catalyst is reported. The new bimetallic chiral salen CoIII complex bearing La(OTf)3 was prepared in a one-pot procedure by activation and bimetallic complex formation from the inactive Jacobsen chiral salen CoII complex (salen = N, N′-bis(3,5-di-tert-butylsalicylidene)-1,2- cyclohexane-diamine). We observed that C1-symmetric chiral bimetallic Co-complex coordinated with La(OTf)3 works as a chiral catalyst and remarkably increased the reactivity and enantioselectivity in the hydrolytic kinetic resolution of terminal epoxides compared to its monometallic analogues. La(OTf)3 plays a crucial role as an achiral Lewis acid in this process, which is supported by the experimental observation presented. To explore the absolute configuration of glycidyl butyrate a vibrational circular dichroism (VCD) spectra was calculated using density functional theory.1 aPatel, D.1 aThakur, S., S.1 aShinde, S., S.1 aKumar, P.  uhttps://library.ncl.res.in/content/catalytic-and-efficient-synthesis-optically-active-terminal-epoxides-and-12-diols-using-new