01145nas a2200145   4500008004100000245015900041210006900200260000800269300001400277490000600291520054100297100002000838700001900858856012200877       2019                        eng d00aStudies toward the total synthesis of parvifolals A/B: an intramolecular o-quinone methide [4 + 2]-cycloaddition to construct the central tetracyclic core0 aStudies toward the total synthesis of parvifolals AB an intramol  cJAN  a810–8180 v43 a<p>Two different approaches funded upon the intramolecular [4 + 2]-cycloaddition of in situ generated o-quinone methides have been explored to construct the central tetracyclic core of parvifolals A/B. At the outset, a cross-pinacol coupling of 2-formyl tri-O-methyl resveratrol with 4-methoxysalicylaldehyde followed by acid treatment was found to provide the desired tetracyclic core with an internal olefin. The requisite pendant aryl group has been introduced by a Pd-catalyzed direct coupling of corresponding diazonium salt.</p>
1 aPaymode, D., J.1 aRamana, C., V.  uhttps://library.ncl.res.in/content/studies-toward-total-synthesis-parvifolals-ab-intramolecular-o-quinone-methide-4-2