01598nas a2200205   4500008004100000022001400041245011200055210006900167260000800236300001100244490000600255520088300261653001301144653001801157653002101175653001701196100002201213700002501235856013201260       2018                        eng d  a2054-570300aPhotophysical studies on curcumin-sophorolipid nanostructures: applications in quorum quenching and imaging0 aPhotophysical studies on curcuminsophorolipid nanostructures app  cFEB  a1708650 v53 a<p>Sophorolipid biosurfactants are biodegradable, less toxic and FDA approved. The purified acidic form of sophorolipid is stimuli-responsive with self-assembling properties and used for solubilizing hydrophobic drugs. This study encapsulated curcumin (CU) with acidic sophorolipid (ASL) micelles and analysed using photophysical studies like UV-visible spectroscopy, photoluminescence (PL) spectroscopy and timecorrelated single photon counting (TCSPC). TEM images have revealed ellipsoid micelles of approximately 100nm size and were confirmed by dynamic light scattering. The bacterial fluorescence uptake studies showed the uptake of formed CUASL nanostructures into both Gram-positive and Gram-negative bacteria. They also showed quorum quenching activity against Pseudomonas aeruginosa. The results have demonstrated this system has potential theranostic applications.</p>10acurcumin10aphotophysical10aQuorum quenching10aSophorolipid1 aVasudevan, Sahana1 aPrabhune, Asmita, A.  uhttps://library.ncl.res.in/content/photophysical-studies-curcumin-sophorolipid-nanostructures-applications-quorum-quenching-and