01162nas a2200193   4500008004100000245007600041210006900117260000800186300001400194490000700208520049700215100002300712700001900735700001500754700002400769700003000793700003700823856010800860       2018                        eng d00aLipase catalyzed synthesis of antimicrobial andrographolide derivatives0 aLipase catalyzed synthesis of antimicrobial andrographolide deri  cJUN  a1134-11410 v183 aIn this data article we describe screening of various lipases for the regioselective acylation of Andrographolide. Each lipase was screened with seven acyl donors. Amano lipase AK from Pseudomonas fluorescens was used for the synthesis of two new acylated andrographolide derivatives. Two new compounds, andrographolide-14-propionate and andrographolide-14-caproate were characterized by various spectral studies. These two derivatives showed more antimicrobial activity than andrographolide.1 aPatil, Harshal, S.1 aJadhav, Dipesh1 aPaul, Ajay1 aMulani, Fayaj, Alam1 aKaregaonkar, Shrikant, J.1 aThulasiram, Hirekodathakallu, V.  uhttps://library.ncl.res.in/content/lipase-catalyzed-synthesis-antimicrobial-andrographolide-derivatives