01121nas a2200145   4500008004100000245012900041210006900170260000800239300001600247490000600263520053500269100002200804700002400826856012500850       2017                        eng d00aSynthesis of succinimide derivatives by NHC-catalyzed stetter reaction of aromatic aldehydes with N-substituted itaconimides0 aSynthesis of succinimide derivatives by NHCcatalyzed stetter rea  cOCT  a6598–66040 v23 a<p>An N-heterocyclic carbene-catalyzed intermolecular Stetter reaction of aromatic aldehydes with N-substituted itaconimides has been developed. A delicate balance between the Stetter reaction and the competing isomerization of the itaconimide double bond has been achieved in this operationally simple reaction to afford valuable new succinimide derivatives containing 1,4 and 1,5 dicarbonyl scaffolds in good to excellent yields. The reaction tolerates variable substituents on both aldehydes and N-substituted itaconimides.</p>1 aAhire, Milind, M.1 aMhaske, Santosh, B.  uhttps://library.ncl.res.in/content/synthesis-succinimide-derivatives-nhc-catalyzed-stetter-reaction-aromatic-aldehydes-n