01469nas a2200181   4500008004100000245010400041210006900145260000800214300001200222490000600234520081300240100002001053700001801073700003101091700001801122700001701140856013001157       2017                        eng d00aDiverse profiles of N-acyl-homoserine lactones in biofilm forming isolates of Cronobacter sakazakii0 aDiverse profiles of Nacylhomoserine lactones in biofilm forming   cOCT  a275-2810 v83 a<p>The present study investigates the role of quorum sensing (QS) molecules expressed by C. sakazakii in biofilm formation and extracellular polysaccharide expression. The QS signaling was detected using Chromobacterium violaceum 026 and Agrobacterium tumefaciens NTL4(pZLR4) based bioassay. Long chain N-acyl-homoserine lactones (AHLs) with C6- C18 chain length were identified using High Performance Liquid Chromatography and Liquid Chromatography-High Resolution Mass Spectrometry. A higher Specific Biofilm Formation (SBF) index (p &lt; 0.05) with the presence of genes associated with cellulose biosynthesis (bcsA, bcsC and bcsG) was observed in the strains. AHLs and their mechanisms can serve as novel targets for developing technologies to eradicate and prevent biofilm formation by C. sakazakii.</p>1 aSingh, Niharika1 aPatil, Amrita1 aPrabhune, Asmita, Ashutosh1 aRaghav, Mamta1 aGoel, Gunjan  uhttps://library.ncl.res.in/content/diverse-profiles-n-acyl-homoserine-lactones-biofilm-forming-isolates-cronobacter-sakazakii