01429nas a2200289 4500008004100000022001400041245008100055210006300136260000800199490000700207520052100214653002200735653001300757653003100770653001700801653001200818653002800830653002300858653002600881653002500907653002900932100002600961700002000987700001501007700001901022856009801041 2017 eng d a1359-734500aC(sp(3))-F, C(sp(2))-F and C(sp(3))-H bond activation at silicon(II) centers0 aCsp3F Csp2F and Csp3H bond activation at siliconII centers cSEP0 v533 a

Silylene [PhC(NtBu)(2)SiN(SiMe3)(2)] (1) cleaves the C(sp(3))-H and C-F bonds of acetophenone and 1,1,1-trifluoroacetophenone, respectively, under mild conditions. The reaction is initiated via a nucleophilic attack from the oxygen to the silicon atom followed by C-F/H bond cleavage. The scope of C-F bond activation has further been extended with C6F6 and C6F5CF3.

10aBoron triple bond10aC-F Bond10aFluorinated Building-Block10aH Activation10aKetones10aN-heterocyclic carbenes10aOxodative Addition10aPerfluorinated Arenes10aSelective Activation10aTransition-Metal Centers1 aSwamy, V., S. V. S. N1 aParvin, Nasrina1 aRaj, Vipin1 aSen, Sakya, S. uhttps://library.ncl.res.in/content/csp3-f-csp2-f-and-csp3-h-bond-activation-siliconii-centers