01354nas a2200157   4500008004100000245008800041210007100129260000800200300001400208490000700222520078100229100002201010700001801032700002001050856012601070       2017                        eng d00aExpeditious and solvent-free nickel-catalyzed C−H arylation of arenes and indoles0 aExpeditious and solventfree nickelcatalyzed C−H arylation of are  cAPR  a2242-22480 v103 aAn efficient solvent-free nickel-catalyzed method for C−H bond arylation of arenes and indoles has been developed, which proceeds expeditiously through chelation assistance. The reaction is highly selective for mono-arylation and tolerates sensitive and structurally diverse functionalities, such as halides, ethers, amines, indole, pyrrole and carbazole. This reaction represents the first example of a nickel-catalyzed C−H arylation by monochelate assistance and symbolizes a rare precedent in solvent-free C−H arylation. Mechanistic investigations by various controlled reactions, kinetic studies, and deuterium labeling experiments suggest that the arylation follows a single electron transfer (SET) pathway involving the turnover-limiting C−H nickelation process.1 aJagtap, Rahul, A.1 aSoni, Vineeta1 aPunji, Benudhar  uhttps://library.ncl.res.in/content/expeditious-and-solvent-free-nickel-catalyzed-c%E2%88%92h-arylation-arenes-and-indoles