00912nas a2200157 4500008004100000245008000041210006900121260000800190300001600198490000700214520036100221100002000582700002200602700001900624856011100643 2009 eng d00aCopper-catalyzed synthesis of 2-unsubstituted, n-substituted benzimidazoles0 aCoppercatalyzed synthesis of 2unsubstituted nsubstituted benzimi cNOV a9570–95720 v743 a

An efficient copper-catalyzed intramolecular arylation of formamidines forming 2-unsubstituted benzimidazoles in excellent yields is reported. Sixteen examples bearing sterically demanding substituents on nitrogen like Mes, 2,6-diisopropylphenyl, or 2-tert-butylphenyl and tolerating various functional groups demonstrate the utility of this method.

1 aHirano, Keiichi1 aBiju, Akkattu, T.1 aGlorius, Frank uhttps://library.ncl.res.in/content/copper-catalyzed-synthesis-2-unsubstituted-n-substituted-benzimidazoles