01353nas a2200205   4500008004100000022001400041245010200055210006900157260007100226300001400297490000700311520055800318100001800876700002700894700002500921700002600946700002400972700002100996856013001017       2016                        eng d  a1523-706000aTotal synthesis of the marine natural product solomonamide B necessitates stereochemical revision0 aTotal synthesis of the marine natural product solomonamide B nec  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcJUL  a3178-31810 v183 a<p>The first total synthesis of the proposed structure of solomonamide B has been achieved. However, the H-1 and C-13 NMR spectral data of the synthesized compound was not exactly matching with that of the natural solomonamide B. This prompted us to revise the originally proposed structure, in particular, the stereochemistry of the nonpeptide part, which was confirmed by its total synthesis. During the course of the synthesis, we have developed an interesting hydroxy group directed Wacker oxidation of internal olefins in a macrocyclic setting.</p>1 aKashinath, K.1 aJachak, Gorakhnath, R.1 aAthawale, Paresh, R.1 aMarelli, Udaya, Kiran1 aGonnade, Rajesh, G.1 aReddy, Srinivasa  uhttps://library.ncl.res.in/content/total-synthesis-marine-natural-product-solomonamide-b-necessitates-stereochemical-revision