01445nas a2200229   4500008004100000022001400041245010200055210006900157260010600226300001400332490000700346520057400353653001800927653002500945653002500970653002000995653001501015100002401030700002101054700002101075856011901096       2016                        eng d  a0040-403900aMulti-gram scale synthesis of hunanamycin A, an antibiotic natural product from the marine source0 aMultigram scale synthesis of hunanamycin A an antibiotic natural  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAUG  a3662-36630 v573 a<p>A simple, practical, and biomimetic approach to access antibiotic natural product hunanamycin A starting from readily available inexpensive material Riboflavin is disclosed here. The present synthesis consists of three operationally simple, protecting group free steps and it is far superior when compared with the previous route. Using this route one can make multi-gram quantities of the natural product which will help in further biological assays, in particular exploring the potential of treating food infections. (C) 2016 Elsevier Ltd. All rights reserved.</p>10aAntibacterial10aBiomimetic synthesis10aGram scale synthesis10aNatural product10aRiboflavin1 aShingare, Rahul, D.1 aFarhana, Sa, Ada1 aReddy, Srinivasa  uhttps://library.ncl.res.in/content/multi-gram-scale-synthesis-hunanamycin-antibiotic-natural-product-marine-source