01445nas a2200205   4500008004100000022001400041245009200055210006900147260011000216300001600326490000600342520063800348100001400986700002201000700002301022700002601045700002401071700002801095856011601123       2014                        eng d  a2046-206900aProbing the folding induction ability of orthanilic acid in peptides: some observations0 aProbing the folding induction ability of orthanilic acid in pept  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJAN  a13018-130250 v43 a<p>This paper describes the ability of orthanilic acid (2-aminobenzenesulfonic acid, (S)Ant) to promote folding when introduced in a peptide sequence. Three peptide sequences, containing orthanilic acid (SAnt) with a sulfonamide moiety in the turn segment, have been synthesized in the solution phase using suitable coupling agents, and their structural aspects investigated using NMR and X-ray crystallographic studies. Solid- and solution-state conformational analyses reveal that the peptide sequences containing orthanilic acid in their backbone exist in a folded conformation featuring long-range 15-membered ring H-bonding.</p>1 aRoy, Arup1 aKotmale, Amol, S.1 aGawade, Rupesh, L.1 aPuranik, Vedavati, G.1 aRajamohanan, P., R.1 aSanjayan, Gangadhar, J.  uhttps://library.ncl.res.in/content/probing-folding-induction-ability-orthanilic-acid-peptides-some-observations