01636nas a2200253   4500008004100000022001400041245015900055210006900214260010600283300001400389490000700403520065300410653001301063653001301076653001501089653002101104653001401125100001901139700002301158700002101181700002401202700002501226856013101251       2005                        eng d  a0040-402000aSulfonate protecting groups. synthesis of O- and C-methylated inositols: D- and L-ononitol, D- and L-laminitol, mytilitol and scyllo-inositol methyl ether0 aSulfonate protecting groups synthesis of O and Cmethylated inosi  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAY  a4437-44460 v613 a<p>Syntheses of D- and L-ononitol, D- and L-laminitol, mytilitol and scyllo-inositol methyl ether starting from myo-imositol are described. One or two of the inyo-inositol 1,3,5-orthoformate hydroxyl groups were protected as tosylates. These mono or ditosylates served as key intermediates for the preparation of O- and C-methyl inositols. Racemic 2,4-di-O-tosyl-myo-inositol 1,3,5-orthoformate was resolved as its diastereomeric camphanates. Use of sulfonate groups for the protection of inositol hydroxyl groups resulted in substantial improvement in the overall yield of O- and C-methyl inositols. (c) 2005 Elsevier Ltd. All rights reserved.</p>10aCyclitol10aInositol10aOrthoester10aProtecting group10asulfonate1 aSarmah, M., P.1 aShashidhar, M., S.1 aSureshan, K., M.1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.  uhttps://library.ncl.res.in/content/sulfonate-protecting-groups-synthesis-o-and-c-methylated-inositols-d-and-l-ononitol-d-and-0