01355nas a2200193   4500008004100000022001400041245015500055210006900210260007100279300001400350490000700364520056600371100001700937700002100954700002200975700002500997700002501022856011401047       2005                        eng d  a0022-326300aSynthesis and intramolecular nitrile oxide cycloaddition of 3,5 `-ether-linked pseudooligosaccharide derivatives: an approach to chiral macrooxacycles0 aSynthesis and intramolecular nitrile oxide cycloaddition of 35 e  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcOCT  a8579-85820 v703 a<p>[GRAPHIC] 3,5'-Ether-linked pseudooligopentose derivatives were synthesized for the first time from readily available carbohydrate precursors. The 1,2-isopropylidene-protected ether-linked oligopentoses are potentially important as precursors of novel RNA analogues. Intramolecular cycloaddition of the nitrile oxides prepared from these derivatives led to the diastereoselective formation of chiral isoxazolines fused to 10-16-membered oxacycles. The stereochemistry of some of these isoxazolines was established by X-ray diffraction and NOESY analysis.</p>1 aSengupta, J.1 aMukhopadhyay, R.1 aBhattacharjya, A.1 aBhadbhade, Mohan, M.1 aBhosekar, Gaurav, V.  uhttps://library.ncl.res.in/content/synthesis-and-intramolecular-nitrile-oxide-cycloaddition-35-ether-linked-1