01654nas a2200181   4500008004100000022001400041245009200055210006900147260007200216300001400288490000700302520095000309100002101259700001901280700002601299700002101325856012601346       2005                        eng d  a1367-480300aIdentification of coding and non-coding sequences using local holder exponent formalism0 aIdentification of coding and noncoding sequences using local hol  aGREAT CLARENDON ST, OXFORD OX2 6DP, ENGLANDbOXFORD UNIV PRESScOCT  a3818-38230 v213 a<p>Motivation: Accurate prediction of genes in genomes has always been a challenging task for bioinformaticians and computational biologists. The discovery of existence of distinct scaling relations in coding and non-coding sequences has led to new perspectives in the understanding of the DNA sequences. This has motivated us to exploit the differences in the local singularity distributions for characterization and classification of coding and non-coding sequences. Results: The local singularity density distribution in the coding and non-coding sequences of four genomes was first estimated using the wavelet transform modulus maxima methodology. Support vector machines classifier was then trained with the extracted features. The trained classifier is able to provide an average test accuracy of 97.7%. The local singularity features in a DNA sequence can be exploited for successful identification of coding and non-coding sequences.</p>1 aKulkarni, O., C.1 aVigneshwar, R.1 aJayaraman, Valadi, K.1 aKulkarni, B., D.  uhttps://library.ncl.res.in/content/identification-coding-and-non-coding-sequences-using-local-holder-exponent-formalism-0