01888nas a2200229   4500008004100000022001400041245016200055210006900217260007700286300001400363490000700377520095900384653002301343653002301366653001901389653002601408653002901434100001701463700002401480700002201504856013201526       2008                        eng d  a0947-653900apK(a)-Directed host-guest assemblies: rational analysis of molecular adducts of 2,4-diamino-6-methyl-1,3,5-triazine with various aliphatic dicarboxylic acids0 apKaDirected hostguest assemblies rational analysis of molecular   aPO BOX 10 11 61, D-69451 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUL  a6967-69770 v143 a<p>Molecular adducts of 2,4-diamino-6-methyl-1,3,5-triazine (1) have been prepared with various aliphatic dicarboxylic acids. The molecular complexes (1a-1i) thus formed by co-crystallizing 1 with oxalic, malonic, succinic, fumaric, acetylene dicarboxylic, glutaric, thiodiglycolic, diglycolic, and adipic acids have been found to give two types of host-guest assemblies that have voids or channels in a three-dimensional arrangement. The different types of host-guest arrangement appear to result from differences in the acidity of the dicarboxylic acids, that is, acids with pK(a) &lt; 3.0 give host networks that consist of 1 and the corresponding acid with water or solvent molecules of crystallization present as guests, whereas acids with pK(a) &gt; 3.0 exist as guests in voids in a host network formed by 1. The former arrangement is observed in adducts 1a, 1b, 1c, and 1h and the latter arrangement is found in adducts 1c, 1d, 1f, 1g and 1i.</p>10adicarboxylic acids10ahost-guest systems10ahydrogen bonds10amolecular recognition10asupramolecular chemistry1 aDelori, Amit1 aSuresh, Eringathodi1 aPedireddi, V., R.  uhttps://library.ncl.res.in/content/pka-directed-host-guest-assemblies-rational-analysis-molecular-adducts-24-diamino-6-methyl-0