01337nas a2200205   4500008004100000022001400041245009700055210006900152260010600221300001400327490000700341520051900348100002500867700002100892700002200913700001900935700002400954700002600978856012701004       2008                        eng d  a0960-894X00aSynthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole0 aSynthesis and antimicrobial activity of betalactambile acid conj  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a2043-20470 v183 a<p>Synthesis of novel 1,2,3-triazole-linked beta-lactam-bile acid conjugates 17-24 using 1,3-dipolar cycloaddition reaction of azido beta-lactam and terminal alkyne of bile acids in the presence of Cu( I) catalyst ( click chemistry) have been realized. These molecules were evaluated in vitro for their antifungal and antibacterial activities. Most of the compounds exhibited significant antifungal and moderate antibacterial activity against all the tested strains. (c) 2008 Elsevier Ltd. All rights reserved.</p>1 aVatmurge, Namdev, S.1 aHazra, Braja, G.1 aPore, Vandana, S.1 aShirazi, Fazal1 aChavan, Pradnya, S.1 aDeshpande, Mukund, V.  uhttps://library.ncl.res.in/content/synthesis-and-antimicrobial-activity-beta-lactam-bile-acid-conjugates-linked-triazole-0