01641nas a2200205   4500008004100000022001400041245015300055210006900208260007300277300001200350490000700362520077800369653001401147653001901161653004801180100002501228700002501253700002601278856013101304       2008                        eng d  a1350-417700aUltrasound promoted copper-, ligand- and amine-free synthesis of benzo[b]furans/nitro benzo[b]furans via Sonogashira coupling-5-endo-dig-cyclization0 aUltrasound promoted copper ligand and aminefree synthesis of ben  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJUL  a853-8620 v153 a<p>This method describes the results of the optimized conditions for the one-pot synthesis of benzo[b]furans/nitro benzo[b]furans via Sonogashira coupling-5-endo-dig-cyclization under ultrasonic irradiation at ambient temperature in the absence of copper, ligand and amine. The protocol tolerates wide range of functional groups present in both the coupling components, especially base labile nitro group was not affected under these mild conditions giving excellent yields of the nitro benzo[b]furans. The formation of Pd(0) nanoparticles as the active species has been shown by TEM analysis and the unique role of ultrasound in promoting the total sonochemical protocol has been substantiated by way of control experiments. (C) 2007 Elsevier B.V. All rights reserved.</p>10a1-alkynes10abenzo[b]furans10aSonogashira coupling-5-endo-dig-cyclization1 aPalimkar, Sanjay, S.1 aMore, Vijaykumar, S.1 aSrinivasan, Kumar, V.  uhttps://library.ncl.res.in/content/ultrasound-promoted-copper-ligand-and-amine-free-synthesis-benzobfuransnitro-benzobfurans-0