01836nas a2200241   4500008004100000022001400041245017800055210006900233260009500302300001200397490000700409520087500416653001801291653002701309653001901336653002201355653001101377653001701388100002301405700001801428700002601446856012201472       2008                        eng d  a0022-201100aT-antigen binding lectin with antibacterial activity from marine invertebrate, sea cucumber (Holothuria scabra): possible involvement in differential recognition of bacteria0 aTantigen binding lectin with antibacterial activity from marine   a525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USAbACADEMIC PRESS INC ELSEVIER SCIENCEcOCT  a141-1450 v993 a<p>In invertebrates, cellular and humoral components are evolved to maintain their body immunity and integrity. Both these factors respond to different antigens such as microorganisms, vertebrate erythrocytes and foreign proteins. In this article, we report a study of a lectin (HSL) involved in immune response in the echinoderm, sea Cucumber (Holothuria scabra). Correlative studies indicate that the expression of this defensive lectin is induced by bacterial challenge, wherein cell wall glycoconjugates of bacteria are involved in lectin induction. HSL showed strong broad spectrum antibacterial activity against both gram-positive and gram-negative bacteria. Under in vitro conditions, purified HSL mediate agglutination of the test bacteria, there by indicating a possible mode of action in physiological situation. (c) 2008 Elsevier Inc. All rights reserved.</p>10aagglutination10aantibacterial activity10acoelomic fluid10aHolothuria scabra10aLectin10asea cucumber1 aGowda, Nagaraj, M.1 aGoswami, Usha1 aKhan, Mohammad, Islam  uhttps://library.ncl.res.in/content/t-antigen-binding-lectin-antibacterial-activity-marine-invertebrate-sea-cucumber-0