01420nas a2200169   4500008004100000022001400041245017400055210006900229260011000298300001400408490000600422520064300428100002201071700002601093700001901119856011201138       2011                        eng d  a1477-052000aRegio- and stereoselective selenium dioxide allylic oxidation of (E)-dialkyl alkylidenesuccinates to (Z)-allylic alcohols: synthesis of natural and unnatural butenolides0 aRegio and stereoselective selenium dioxide allylic oxidation of   aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJUN  a6312-63220 v93 a<p>The first SeO(2) induced (Z)-selective allylic alcohol formation of dialkyl alkylidenesuccinates has been demonstrated to accomplish one-step syntheses of several essential butenolides and fused butenolides via an unusual E- to Z- carbon-carbon double bond isomerisation followed by the lactonization pathway. The observed regio- and stereoselective SeO(2) allylic oxidation protocol has also been extended to the diastereoselective total synthesis of bioactive natural product isomintlactone, its direct conversion to mintlactone and an example of the base-catalyzed intramolecular rearrangement of gamma-lactone to delta-lactone.</p>1 aPatel, Ramesh, M.1 aPuranik, Vedavati, G.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/regio-and-stereoselective-selenium-dioxide-allylic-oxidation-e-dialkyl-0