02036nas a2200241   4500008004100000022001400041245009900055210006900154260009900223300001400322490000800336520113800344653002401482653002401506653001201530653001601542653002501558100002201583700002001605700002801625700002001653856012101673       2011                        eng d  a0960-852400aDevelopment of biocatalysts for production of commodity chemicals from lignocellulosic biomass0 aDevelopment of biocatalysts for production of commodity chemical  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLANDbELSEVIER SCI LTDcMAR  a4304-43120 v1023 a<p>Lignocellulosic biomass is recognized as potential sustainable source for production of power, biofuels and variety of commodity chemicals which would potentially add economic value to biomass. Recalcitrance nature of biomass is largely responsible for the high cost of its conversion. Therefore, it is necessary to introduce some cost effective pretreatment processes to make the biomass polysaccharides easily amenable to enzymatic attack to release mixed fermentable sugars. Advancement in systemic biology can provide new tools for the development of such biocatalysts for sustainable production of commodity chemicals from biomass. Integration of functional genomics and system biology approaches may generate efficient microbial systems with new metabolic routes for production of commodity chemicals. This paper provides an overview of the challenges that are faced by the processes converting lignocellulosic biomass to commodity chemicals. The critical factors involved in engineering new microbial biocatalysts are also discussed with more emphasis on commodity chemicals. (C) 2011 Elsevier Ltd. All rights reserved.</p>10aBiomass utilization10aCommodity chemicals10aEthanol10aLactic acid10aMicrobial cellulases1 aAdsul, Mukund, G.1 aSinghvi, M., S.1 aGaikaiwari, Shalaka, A.1 aGokhale, D., V.  uhttps://library.ncl.res.in/content/development-biocatalysts-production-commodity-chemicals-lignocellulosic-biomass-0