01503nas a2200265   4500008004100000022001400041245012700055210006900182260010300251300001400354490000700368520047800375653002700853653002400880653002200904653002300926653002200949100002600971700002200997700002401019700002201043700001901065700002601084856012701110       2011                        eng d  a0223-523400aStereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain0 aStereoselective synthesis and antimicrobial activity of steroida  a23 RUE LINOIS, 75724 PARIS, FRANCEbELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERcSEP  a3681-36890 v463 a<p>Stereoselective synthesis of novel steroidal C-20 tertiary alcohols with thiazole and pyridine side chain using Grignard reaction of steroidal ketones and thiazole/pyridine magnesium bromide have been realized. These molecules were evaluated in vitro for their antifungal and antibacterial activities. Most of the compounds exhibited significant antifungal and antibacterial activity against all the tested strains. (C) 2011 Elsevier Masson SAS. All rights reserved.</p>10aantibacterial activity10aAntifungal activity10aGrignard reaction10aSteroid side chain10aSteroidal ketones1 aShingate, Bapurao, B.1 aLiazra, Braja, G.1 aSalunke, Deepak, B.1 aPore, Vandana, S.1 aShirazi, Fazal1 aDeshpande, Mukund, V.  uhttps://library.ncl.res.in/content/stereoselective-synthesis-and-antimicrobial-activity-steroidal-c-20-tertiary-alcohols-0