01741nas a2200181   4500008004100000022001400041245011500055210006900170260007600239300001200315490000700327520100800334653002601342653002701368100002001395700001701415856012701432       2012                        eng d  a0192-865100aNew approximate method for the stochastic simulation of chemical systems: the representative reaction approach0 aNew approximate method for the stochastic simulation of chemical  aCOMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USAbWILEY-BLACKWELLcJAN  a276-2850 v333 a<p>We have developed two new approximate methods for stochastically simulating chemical systems. The methods are based on the idea of representing all the reactions in the chemical system by a single reaction, i.e., by the representative reaction approach (RRA). Discussed in the article are the concepts underlying the new methods along with flowchart with all the steps required for their implementation. It is shown that the two RRA methods {with the reaction \$ 2A \textbackslashrightarrow B \$ as the representative reaction (RR)} perform creditably with regard to accuracy and computational efficiency, in comparison to the exact stochastic simulation algorithm (SSA) developed by Gillespie and are able to successfully reproduce at least the first two moments of the probability distribution of each species in the systems studied. As such, the RRA methods represent a promising new approach for stochastically simulating chemical systems. (C) 2011 Wiley Periodicals, Inc. J Comput Chem, 2012</p>10aapproximate algorithm10aStochastic simulations1 aKadam, Shantanu1 aVanka, Kumar  uhttps://library.ncl.res.in/content/new-approximate-method-stochastic-simulation-chemical-systems-representative-reaction-0