01237nas a2200169   4500008004100000022001400041245005600055210005500111260007200166300001200238490000700250520066300257100001700920700002400937700002100961856008500982       2012                        eng d  a1367-480300aClare: cracking the language of regulatory elements0 aClare cracking the language of regulatory elements  aGREAT CLARENDON ST, OXFORD OX2 6DP, ENGLANDbOXFORD UNIV PRESScFEB  a581-5830 v283 a<p>CLARE is a computational method designed to reveal sequence encryption of tissue- specific regulatory elements. Starting with a set of regulatory elements known to be active in a particular tissue/process, it learns the sequence code of the input set and builds a predictive model from features specific to those elements. The resulting model can then be applied to user-supplied genomic regions to identify novel candidate regulatory elements. CLARE's model also provides a detailed analysis of transcription factors that most likely bind to the elements, making it an invaluable tool for understanding mechanisms of tissue- specific gene regulation.</p>1 aTaher, Leila1 aNarlikar, Leelavati1 aOvcharenko, Ivan  uhttps://library.ncl.res.in/content/clare-cracking-language-regulatory-elements-0