01581nas a2200193   4500008004100000022001400041245007100055210006700126260011000193300001400303490000600317520085700323100002301180700001901203700002001222700002201242700003001264856009301294       2013                        eng d  a2046-206900aDevelopment of a multifunctional catalyst for a ``relay'' reaction0 aDevelopment of a multifunctional catalyst for a relay reaction  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcDEC  a2186-21910 v33 a<p>In the area of catalysis, nanoparticles and enzymes are two of the most important systems. By amalgamating the two, we present here proof of the concept that it is possible to prepare a multifunctional catalyst that can carry out a ``relay'' reaction. The catalyst consists of a surface bound enzyme on a metal(core)-silica(shell) nanoparticle architecture. Here the enzyme catalyzes the 1st reaction and the metal nanoparticles act as a catalyst for the 2nd reaction of the product from the 1st reaction. In particular, we have studied the catalytic activity of glucosidase grafted Au@mSiO(2) on 4-nitrophenyl-beta-glucopyranoside, where glucosidase will catalyse the 1st step to generate 4-nitrophenol, which acts as a substrate for the next reduction step which is catalysed by the Au nanoparticles present inside the mesoporous silica shell.</p>1 aGanai, Anal, Kumar1 aShinde, Pravin1 aDhar, Basab, B.1 aGupta, Sayam, Sen1 aPrasad, Bhagavatula L. V.  uhttps://library.ncl.res.in/content/development-multifunctional-catalyst-relay-reaction-0