01323nas a2200169   4500008004100000022001400041245024400055210006900299260011000368300001600478490000600494520044900500100003100949700002700980700002401007856012201031       2013                        eng d  a2046-206900aNovel and efficient synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via sp(3) C-H functionalization of 2-methyl azaarenes and (2-azaaryl)methanes over a heterogeneous, reusable silica-supported dodecatungstophosphoric acid catalyst0 aNovel and efficient synthesis of azaarenesubstituted 3hydroxy2ox  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG  a20281-202860 v33 a<p>A novel and efficient protocol has been developed for the synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via sp(3) C-H functionalization of 2-methyl azaarenes and (2-azaaryl)methanes with isatin in good to excellent yield. This is the first example in which heterogeneous, reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) catalyzed sp(3) C-H functionalization of 2-substituted azaarenes and (2-azaaryl)methanes.</p>1 aMulla, Shafeek, Abdul Rash1 aPathan, Mohsinkhan, Y.1 aChavan, Santosh, S.  uhttps://library.ncl.res.in/content/novel-and-efficient-synthesis-azaarene-substituted-3-hydroxy-2-oxindoles-sp3-c-h-0