01272nas a2200157   4500008004100000022001400041245009600055210006900151260010600220300001000326490000700336520059900343100002500942700002800967856011900995       2013                        eng d  a0957-416600aSystematic evaluation of a few proline derivatives as catalysts for a direct aldol reaction0 aSystematic evaluation of a few proline derivatives as catalysts   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a43-490 v243 a<p>A series of pyrrolidine derivatives were prepared and examined as catalysts for an aldol reaction. Structural variations in these molecules involved altering the sterics at the alpha-position, the position of the carbonyl group, and the acidities of the hydrogen bonding sites. The effect of these factors on catalytic activity and enantioselectivity was studied. The experimental results revealed that additional sterics at the alpha-position were detrimental. However, no correlation was found between the catalytic activity and N-H acidity. (C) 2012 Elsevier Ltd. All rights reserved.</p>1 aSutar, Revannath, L.1 aJoshi, Navalkishore, N.  uhttps://library.ncl.res.in/content/systematic-evaluation-few-proline-derivatives-catalysts-direct-aldol-reaction-0