02014nas a2200217   4500008004100000022001400041245007600055210006900131260006700200300001200267490000700279520124500286653002301531653001401554653001601568653003301584653003301617100001901650700002601669856010101695       2013                        eng d  a8756-793800aChitinolytic enzymes: an appraisal as a product of commercial potential0 aChitinolytic enzymes an appraisal as a product of commercial pot  a111 RIVER ST, HOBOKEN 07030-5774, NJ USAbWILEY-BLACKWELLcJUL  a833-8460 v293 a<p>Chitin, its deacetylated form, chitosan and chitinolytic enzymes viz. endo-chitinase, N-acetylglucosaminidase, chitosanase, chitin deacetylase (CDA) are gaining importance for their biotechnological applications. Presently, chitin degrading enzymes constitute high-cost low-volume products in human health care and associated research. Indeed chitinases and CDA-chitosanase complex possesss tremendous potential in agriculture to control plant pathogenic fungi and insects. The success in exploring chitinases especially for agriculture, i.e. as a high-volume low-cost product, depends on the availability of highly active preparations with a reasonable cost. Therefore, a reconsideration in terms of understanding the roles of chitinolytic enzymes in applications, e.g. host-pathogen interaction for biocontrol, different mechanisms of chitin degradation, and identification of new enzymes with varying specificities, may make them more useful in a variety of commercial processes in the near future. The possible issues and challenges encountered in the translation of proof of concept into a commercial product will be appraised in this review. (c) 2013 American Institute of Chemical Engineers Biotechnol. Prog., 29:833-846, 2013</p>10achitin deacetylase10achitinase10achitosanase10ahigh-cost low-volume product10ahigh-volume low-cost product1 aChavan, S., B.1 aDeshpande, Mukund, V.  uhttps://library.ncl.res.in/content/chitinolytic-enzymes-appraisal-product-commercial-potential-0