01567nas a2200253   4500008004100000022001400041245011200055210006900167260010600236300001200342490000700354520061100361653001700972653001800989653001401007653002801021653002101049100002501070700002101095700002101116700002401137700002601161856012601187       2014                        eng d  a0040-403900aUnexpected observations during the total synthesis of calothrixin B-sodium methoxide as a source of hydride0 aUnexpected observations during the total synthesis of calothrixi  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a155-1620 v553 a<p>During the total synthesis of calothrixin B, various novel and unexpected results were noticed such as cleavage of C-N bond in imine using sodium cyanoborohydride, sodium methoxide as a hydride source for reduction, deformylation in the presence of bromine, and deacylation using ceric ammonium nitrate (CAN). A detailed mechanism has been proposed for the unexpected results and a few of them are generalized. Temperature dependent NMR studies have been carried out for confirmation of the structure of one of the intermediates in the synthetic sequence. (C) 2013 Elsevier Ltd. All rights reserved.</p>10aAzoxybenzene10aCalothrixin B10areduction10aSodium cyanoborohydride10aSodium methoxide1 aBhosale, Shrikar, M.1 aMomin, Aadil, A.1 aKunjir, Shrikant1 aRajamohanan, P., R.1 aKusurkar, Radhika, S.  uhttps://library.ncl.res.in/content/unexpected-observations-during-total-synthesis-calothrixin-b-sodium-methoxide-source-0